This is an analysis and review for 17 cases of multiple myeloma, 1 case of plasma cell
leukemia and 1 case of adult Fanconi syndrome, which have been encountered in. this
laboratory during the last 10 years from 1964 to 1975, July.
The following results are obtained in analysis of 17 cases of multiple myeloma.
1. The sex ratio was predominant in male, being 4.7 : 1 and the mean of age
distribution was 15 years, ranging from 34 to 73 years.
2. The most frequent complaints at the time of admissions were the bony pains (77%)
, sym-ptoms due to anemia (53%), and symptoms due to hyperralcemia (35%).
3. The means of hemoglobin and ESR were 7.5gm% and 62mm/hr, respectively and the
peripheral plasma cells are found in 47% of the cases, ranging 4.5-95% in number of
differential counts.
4. The mean of myeloma cell distributions in bone marrow was 46.3%, ranging from
4.5-95% in number of differential counts.
5. Serum M-components were detected in 10 cases among 13(77%) and 7 cases of
them were known to be IgA (4) and IgG (3) by immuno-electrophoresis or radial
immunodiffusion method.
6. Bence-Jones proteinuria was present in 8 cases (50%) among 16.
7. Multiple punched-out osteolytic lesions were found in 12 cases (85.7%) among 14 by
radio-logical bone series.
The one case of plasma cell leukemia disclosed 76,400/mm3 in W.B.C.
count with 51% of plasma cells in peripheral blood, and the one case of adult Fanconi
syndrome revealed atypical plasmacytosis (10%) in bone marrow, but no M-component
is identified.
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